UCK1 Back

uridine-cytidine kinase 1

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NCBI Description of UCK1
This gene encodes a uridine-cytidine kinase that catalyzes the phosphorylation of uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP) but not the phosphorylation of deoxyribonucleosides or purine ribonucleosides. This enzyme can also phosphorylate uridine and cytidine analogs and uses both ATP and GTP as a phosphate donor. Alternative splicing results in multiple splice variants encoding distinct isoforms.

Community Annotation of UCK1 Add / Edit UCK1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

UCK1 is highly significantly mutated in
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UCK1 is significantly mutated in
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UCK1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for UCK1