UBE2Q1 Back

ubiquitin-conjugating enzyme E2Q (putative) 1

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NCBI Description of UBE2Q1
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is 98% identical to the mouse counterpart. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.

Community Annotation of UBE2Q1 Add / Edit UBE2Q1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

UBE2Q1 is highly significantly mutated in
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UBE2Q1 is significantly mutated in
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UBE2Q1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for UBE2Q1