NCBI Description of UBE2J2
|The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.|
Community Annotation of UBE2J2 Add / Edit UBE2J2: Annotations
No community annotations yet for UBE2J2.
• "Mouse over" a mutation to see details.
Click on a tumor type to see its full list of significant genes.