UBE2G1 Back

ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of UBE2G1
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family and catalyzes the covalent attachment of ubiquitin to other proteins. The protein may be involved in degradation of muscle-specific proteins.

Community Annotation of UBE2G1 Add / Edit UBE2G1: Annotations

No community annotations yet for UBE2G1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

UBE2G1 is highly significantly mutated in
(none)
UBE2G1 is significantly mutated in
(none)
UBE2G1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for UBE2G1