UBA5 Back

ubiquitin-like modifier activating enzyme 5

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NCBI Description of UBA5

This gene encodes a member of the E1-like ubiquitin-activating enzyme family. This protein activates ubiquitin-fold modifier 1, a ubiquitin-like post-translational modifier protein, via the formation of a high-energy thioester bond. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. A pseudogene located on chromosome 1 has also been identified.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

UBA5 is highly significantly mutated in
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UBA5 is significantly mutated in
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UBA5 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for UBA5