UBA2 Back

ubiquitin-like modifier activating enzyme 2

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of UBA2
Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010].

Community Annotation of UBA2 Add / Edit UBA2: Annotations

No community annotations yet for UBA2.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

UBA2 is highly significantly mutated in
(none)
UBA2 is significantly mutated in
(none)
UBA2 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for UBA2