TYW3 Back

tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)

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NCBI Description of TYW3

Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW3 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).[supplied by OMIM, Mar 2008].

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


TYW3 is highly significantly mutated in
TYW3 is significantly mutated in
TYW3 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for TYW3