TYRP1 Back

tyrosinase-related protein 1

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NCBI Description of TYRP1

This gene encodes a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Defects in this gene are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III.

Community Annotation of TYRP1 Add / Edit TYRP1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TYRP1 is highly significantly mutated in
(none)
TYRP1 is significantly mutated in
(none)
TYRP1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for TYRP1