TYRO3 Back

TYRO3 protein tyrosine kinase

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NCBI Description of TYRO3

The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TYRO3 is highly significantly mutated in
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TYRO3 is significantly mutated in
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TYRO3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for TYRO3