TYMP Back

thymidine phosphorylase

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of TYMP

This gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified.

Community Annotation of TYMP Add / Edit TYMP: Annotations

No community annotations yet for TYMP.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TYMP is highly significantly mutated in
(none)
TYMP is significantly mutated in
(none)
TYMP is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for TYMP