TXN2 Back

thioredoxin 2

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NCBI Description of TXN2

This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis.

Community Annotation of TXN2 Add / Edit TXN2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TXN2 is highly significantly mutated in
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TXN2 is significantly mutated in
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TXN2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for TXN2