TWF1 Back

twinfilin, actin-binding protein, homolog 1 (Drosophila)

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NCBI Description of TWF1
This gene encodes twinfilin, an actin monomer-binding protein conserved from yeast to mammals. Studies of the mouse counterpart suggest that this protein may be an actin monomer-binding protein, and its localization to cortical G-actin-rich structures may be regulated by the small GTPase RAC1.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TWF1 is highly significantly mutated in
(none)
TWF1 is significantly mutated in
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TWF1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TWF1