TUSC3 Back

tumor suppressor candidate 3

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NCBI Description of TUSC3

This gene is a candidate tumor suppressor gene. It is located within a homozygously deleted region of a metastatic prostate cancer. The gene is expressed in most nonlymphoid human tissues including prostate, lung, liver, and colon. Expression was also detected in many epithelial tumor cell lines. Two transcript variants encoding distinct isoforms have been identified for this gene.

Community Annotation of TUSC3 Add / Edit TUSC3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TUSC3 is highly significantly mutated in
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TUSC3 is significantly mutated in
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TUSC3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for TUSC3