TUBA8 Back

tubulin, alpha 8

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NCBI Description of TUBA8
This gene encodes a member of the alpha tubulin protein family. Alpha tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. Mutations in this gene are associated with polymicrogyria and optic nerve hypoplasia. Alternate splicing results in multiple transcript variants.

Community Annotation of TUBA8 Add / Edit TUBA8: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TUBA8 is highly significantly mutated in
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TUBA8 is significantly mutated in
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TUBA8 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TUBA8