TTF2 Back

transcription termination factor, RNA polymerase II

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of TTF2

This gene encodes a member of the SWI2/SNF2 family of proteins, which play a critical role in altering protein-DNA interactions. The encoded protein has been shown to have dsDNA-dependent ATPase activity and RNA polymerase II termination activity. This protein interacts with cell division cycle 5-like, associates with human splicing complexes, and plays a role in pre-mRNA splicing.

Community Annotation of TTF2 Add / Edit TTF2: Annotations

No community annotations yet for TTF2.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


TTF2 is highly significantly mutated in
TTF2 is significantly mutated in
TTF2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for TTF2