TTBK2 Back

tau tubulin kinase 2

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NCBI Description of TTBK2
This gene encodes a serine-threonine kinase that putatively phosphorylates tau and tubulin proteins. Mutations in this gene cause spinocerebellar ataxia type 11 (SCA11); a neurodegenerative disease characterized by progressive ataxia and atrophy of the cerebellum and brainstem.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TTBK2 is highly significantly mutated in
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TTBK2 is significantly mutated in
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TTBK2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TTBK2