TSTA3 Back

tissue specific transplantation antigen P35B

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NCBI Description of TSTA3
Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II.

Community Annotation of TSTA3 Add / Edit TSTA3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TSTA3 is highly significantly mutated in
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TSTA3 is significantly mutated in
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TSTA3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TSTA3