TST Back

thiosulfate sulfurtransferase (rhodanese)

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NCBI Description of TST
This is one of two neighboring genes encoding similar proteins that each contain two rhodanese domains. The encoded protein is localized to the mitochondria and catalyzes the conversion of thiosulfate and cyanide to thiocyanate and sulfite. In addition, the protein interacts with 5S ribosomal RNA and facilitates its import into the mitochondria. Alternative splicing results in multiple transcript variants.

Community Annotation of TST Add / Edit TST: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TST is highly significantly mutated in
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TST is significantly mutated in
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TST is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TST