TSPAN3 Back

tetraspanin 3

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NCBI Description of TSPAN3
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The use of alternate polyadenylation sites has been found for this gene. Multiple alternative transcripts encoding different isoforms have been described.

Community Annotation of TSPAN3 Add / Edit TSPAN3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TSPAN3 is highly significantly mutated in
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TSPAN3 is significantly mutated in
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TSPAN3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TSPAN3