TSPAN16 Back

tetraspanin 16

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NCBI Description of TSPAN16

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein might couple to signal transduction pathways and possibly modulate cellular activation and adhesion in haemopoietic and neural tissue. Sequence Note: The sequence AF133424.1 is a chimeric mRNA clone. Only the tetraspanin TM4-B region was propagated into this RefSeq record.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


TSPAN16 is highly significantly mutated in
TSPAN16 is significantly mutated in
TSPAN16 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for TSPAN16