TSKS Back

testis-specific serine kinase substrate

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NCBI Description of TSKS

This gene may play a role in testicular physiology, spermatogenesis or spermiogenesis. Expression of the encoded protein is highest in the testis and down-regulated in testicular cancer. The gene is localized to the region 19q13.3 among the related RAS viral oncogene homolog (RRAS) and interferon regulatory factor 3 (IRF3) genes, which are both involved in tumorigenesis pathways and progression.

Community Annotation of TSKS Add / Edit TSKS: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TSKS is highly significantly mutated in
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TSKS is significantly mutated in
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TSKS is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for TSKS