TSGA14 Back

testis specific, 14

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NCBI Description of TSGA14

This gene encodes a centrosomal and microtubule-binding protein which is predicted to have two coiled-coil domains and a rhodanese domain. In human retinal pigment epithelial cells the protein localized to centrioles and cilia. Mutations in this gene have been associated with Joubert Syndrome 15; an autosomal recessive ciliopathy and neurological disorder. Alternative splicing results in multiple transcript variants.

Community Annotation of TSGA14 Add / Edit TSGA14: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TSGA14 is highly significantly mutated in
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TSGA14 is significantly mutated in
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TSGA14 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for TSGA14