TSFM Back

Ts translation elongation factor, mitochondrial

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NCBI Description of TSFM
This gene encodes a mitochondrial translation elongation factor. The encoded protein is an enzyme that catalyzes the exchange of guanine nucleotides on the translation elongation factor Tu during the elongation step of mitchondrial protein translation. Mutations in this gene are associated with combined oxidative phosphorylation deficiency-3 syndrome. Alternate splicing results in multiple transcript variants.

Community Annotation of TSFM Add / Edit TSFM: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TSFM is highly significantly mutated in
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TSFM is significantly mutated in
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TSFM is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TSFM