TSEN54 Back

tRNA splicing endonuclease 54 homolog (S. cerevisiae)

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NCBI Description of TSEN54
This gene encodes a subunit of the tRNA splicing endonuclease complex, which catalyzes the removal of introns from precursor tRNAs. The complex is also implicated in pre-mRNA 3-prime end processing. Mutations in this gene result in pontocerebellar hypoplasia type 2.

Community Annotation of TSEN54 Add / Edit TSEN54: Annotations

No community annotations yet for TSEN54.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TSEN54 is highly significantly mutated in
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TSEN54 is significantly mutated in
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TSEN54 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TSEN54