TSEN15 Back

tRNA splicing endonuclease 15 homolog (S. cerevisiae)

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NCBI Description of TSEN15

tRNA splicing is a fundamental process required for cell growth and division. SEN15 is a subunit of the tRNA splicing endonuclease, which catalyzes the removal of introns, the first step in tRNA splicing (Paushkin et al., 2004 [PubMed 15109492]).[supplied by OMIM, Mar 2008].

Community Annotation of TSEN15 Add / Edit TSEN15: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


TSEN15 is highly significantly mutated in
TSEN15 is significantly mutated in
TSEN15 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for TSEN15