TRPV5 Back

transient receptor potential cation channel, subfamily V, member 5

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NCBI Description of TRPV5

This gene is a member of the transient receptor family and the TrpV subfamily. The calcium-selective channel encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level.

Community Annotation of TRPV5 Add / Edit TRPV5: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


TRPV5 is highly significantly mutated in
TRPV5 is significantly mutated in
TRPV5 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for TRPV5