NCBI Description of TRPM6
|This gene is predominantly expressed in the kidney and colon, and encodes a protein containing an ion channel domain and a protein kinase domain. It is crucial for magnesium homeostasis, and plays an essential role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. Mutations in this gene are associated with hypomagnesemia with secondary hypocalcemia. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.|
Community Annotation of TRPM6 Add / Edit TRPM6: Annotations
No community annotations yet for TRPM6.
Click on a tumor type to see its full list of significant genes.