TRMT5 Back

TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae)

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NCBI Description of TRMT5

tRNAs contain as many as 13 or 14 nucleotides that are modified posttranscriptionally by enzymes that are highly specific for particular nucleotides in the tRNA structure. TRMT5 methylates the N1 position of guanosine-37 (G37) in selected tRNAs using S-adenosyl methionine (Brule et al., 2004 [PubMed 15248782]).[supplied by OMIM, Mar 2008].

Community Annotation of TRMT5 Add / Edit TRMT5: Annotations

No community annotations yet for TRMT5.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TRMT5 is highly significantly mutated in
(none)
TRMT5 is significantly mutated in
(none)
TRMT5 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for TRMT5