TRMT2B Back

tRNA methyltransferase 2 homolog B (S. cerevisiae)

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NCBI Description of TRMT2B
This gene encodes a homolog of the TRM2 gene in S. cerevisiae. The yeast gene encodes a tRNA methyltransferase that plays a role in tRNA maturation. The yeast protein also has endo-exonuclease activity and may be involved in DNA double strand break repair. Alternative splicing results in multiple transcripts encoding different isoforms.

Community Annotation of TRMT2B Add / Edit TRMT2B: Annotations

No community annotations yet for TRMT2B.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TRMT2B is highly significantly mutated in
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TRMT2B is significantly mutated in
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TRMT2B is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TRMT2B