TRMT12 Back

tRNA methyltransferase 12 homolog (S. cerevisiae)

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NCBI Description of TRMT12
Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TRMT12 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).[supplied by OMIM, Mar 2008].

Community Annotation of TRMT12 Add / Edit TRMT12: Annotations

No community annotations yet for TRMT12.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TRMT12 is highly significantly mutated in
(none)
TRMT12 is significantly mutated in
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TRMT12 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TRMT12