TRIP11 Back

thyroid hormone receptor interactor 11

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NCBI Description of TRIP11
This gene was identified based on the interaction of its protein product with thyroid hormone receptor beta. This protein is associated with the Golgi apparatus. The N-terminal region of the protein binds Golgi membranes and the C-terminal region binds the minus ends of microtubules; thus, the protein is thought to play a role in assembly and maintenance of the Golgi ribbon structure around the centrosome. Mutations in this gene cause achondrogenesis type IA.

Community Annotation of TRIP11 Add / Edit TRIP11: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TRIP11 is highly significantly mutated in
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TRIP11 is significantly mutated in
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TRIP11 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TRIP11