TRIM69 Back

tripartite motif-containing 69

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NCBI Description of TRIM69

This gene encodes a member of the RING-B-box-coiled-coil (RBCC) family and encodes a protein with an N-terminal RING finger motif, a PRY domain and a C-terminal SPRY domain. The mouse ortholog of this gene is specifically expressed in germ cells at the round spermatid stages during spermatogenesis and, when overexpressed, induces apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Community Annotation of TRIM69 Add / Edit TRIM69: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TRIM69 is highly significantly mutated in
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TRIM69 is significantly mutated in
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TRIM69 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for TRIM69