TRIM55 Back

tripartite motif-containing 55

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NCBI Description of TRIM55
The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein associates transiently with microtubules, myosin, and titin during muscle sarcomere assembly. It may act as a transient adaptor and plays a regulatory role in the assembly of sarcomeres. Four alternatively spliced transcript variants encoding distinct isoforms have been described.

Community Annotation of TRIM55 Add / Edit TRIM55: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TRIM55 is highly significantly mutated in
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TRIM55 is significantly mutated in
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TRIM55 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TRIM55