TRIM26 Back

tripartite motif-containing 26

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of TRIM26
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Although the function of the protein is unknown, the RING domain suggests that the protein may have DNA-binding activity. The gene localizes to the major histocompatibility complex (MHC) class I region on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Community Annotation of TRIM26 Add / Edit TRIM26: Annotations

No community annotations yet for TRIM26.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TRIM26 is highly significantly mutated in
(none)
TRIM26 is significantly mutated in
(none)
TRIM26 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TRIM26