NCBI Description of TREX1
|This gene encodes a nuclear protein with 3' exonuclease activity. The encoded protein may play a role in DNA repair and serve as a proofreading function for DNA polymerase. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, Cree encephalitis, and other diseases of the immune system. Alternative splicing results in multiple transcript variants.|
Community Annotation of TREX1 Add / Edit TREX1: Annotations
No community annotations yet for TREX1.
• "Mouse over" a mutation to see details.
Click on a tumor type to see its full list of significant genes.