TREML1 Back

triggering receptor expressed on myeloid cells-like 1

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NCBI Description of TREML1
This gene encodes a member of the triggering receptor expressed on myeloid cells-like (TREM) family. The encoded protein is a type 1 single Ig domain orphan receptor localized to the alpha-granule membranes of platelets. The encoded protein is involved in platelet aggregation, inflammation, and cellular activation and has been linked to Gray platelet syndrome. Alternative splicing results in multiple transcript variants

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TREML1 is highly significantly mutated in
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TREML1 is significantly mutated in
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TREML1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TREML1