TREM1 Back

triggering receptor expressed on myeloid cells 1

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NCBI Description of TREM1
This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Community Annotation of TREM1 Add / Edit TREM1: Annotations

No community annotations yet for TREM1.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TREM1 is highly significantly mutated in
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TREM1 is significantly mutated in
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TREM1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TREM1