TRAP1 Back

TNF receptor-associated protein 1

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NCBI Description of TRAP1

This gene encodes a mitochondrial chaperone protein that is member of the heat shock protein 90 (HSP90) family. The encoded protein has ATPase activity and interacts with tumor necrosis factor type I. This protein may function in regulating cellular stress responses. Alternate splicing results in multiple transcript variants.

Community Annotation of TRAP1 Add / Edit TRAP1: Annotations

No community annotations yet for TRAP1.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TRAP1 is highly significantly mutated in
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TRAP1 is significantly mutated in
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TRAP1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for TRAP1