TRAM1 Back

translocation associated membrane protein 1

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NCBI Description of TRAM1
This gene encodes a multi-pass membrane protein that is part of the mammalian endoplasmic reticulum. The encoded protein influences glycosylation and facilitates the translocation of secretory proteins across the endoplasmic reticulum membrane by regulating which domains of the nascent polypeptide chain are visible to the cytosol during a translocational pause. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

Community Annotation of TRAM1 Add / Edit TRAM1: Annotations

No community annotations yet for TRAM1.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TRAM1 is highly significantly mutated in
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TRAM1 is significantly mutated in
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TRAM1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TRAM1