TPK1 Back

thiamin pyrophosphokinase 1

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NCBI Description of TPK1
This gene encodes a protein, that exists as a homodimer, which catalyzes the conversion of thiamine to thiamine pyrophosphate. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Community Annotation of TPK1 Add / Edit TPK1: Annotations

No community annotations yet for TPK1.
Sort mutations by: Tumor type  Mutation type  Position  
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TPK1 is highly significantly mutated in
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TPK1 is significantly mutated in
(none)
TPK1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TPK1