TP53AIP1 Back

tumor protein p53 regulated apoptosis inducing protein 1

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NCBI Description of TP53AIP1

This gene is specifically expressed in the thymus, and encodes a protein that is localized to the mitochondrion. The expression of this gene is inducible by p53, and it is thought to play an important role in mediating p53-dependent apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


TP53AIP1 is highly significantly mutated in
TP53AIP1 is significantly mutated in
TP53AIP1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for TP53AIP1