TOX Back

thymocyte selection-associated high mobility group box

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NCBI Description of TOX

The protein encoded by this gene contains a HMG box DNA binding domain. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. This protein may function to regulate T-cell development.

Community Annotation of TOX Add / Edit TOX: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


TOX is highly significantly mutated in
TOX is significantly mutated in
TOX is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for TOX