NCBI Description of TOPBP1
|This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands.|
Community Annotation of TOPBP1 Add / Edit TOPBP1: Annotations
No community annotations yet for TOPBP1.
• "Mouse over" a mutation to see details.
Click on a tumor type to see its full list of significant genes.