TNP1 Back

transition protein 1 (during histone to protamine replacement)

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NCBI Description of TNP1
Transition protein-1 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines (see PRM1, MIM 182880; PRM2, MIM 182890) (Luerssen et al., 1990 [PubMed 2249851]).[supplied by OMIM, Mar 2008]. Sequence Note: removed 4 bases from the 5' end that did not align to the reference genome assembly.

Community Annotation of TNP1 Add / Edit TNP1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TNP1 is highly significantly mutated in
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TNP1 is significantly mutated in
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TNP1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TNP1