TNNC2 Back

troponin C type 2 (fast)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of TNNC2
Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn-C subunit.

Community Annotation of TNNC2 Add / Edit TNNC2: Annotations

No community annotations yet for TNNC2.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TNNC2 is highly significantly mutated in
(none)
TNNC2 is significantly mutated in
(none)
TNNC2 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TNNC2