TNIP2 Back

TNFAIP3 interacting protein 2

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NCBI Description of TNIP2

TNIP2 binds to the C-terminal zinc finger domain of A20 (TNFAIP3; MIM 191163) and is involved in activation of the ERK (see MAPK3; MIM 601795) MAP kinase pathway in various cell types (Van Huffel et al., 2001 [PubMed 11390377]; Papoutsopoulou et al., 2006 [PubMed 16633345]).[supplied by OMIM, Mar 2008].

Community Annotation of TNIP2 Add / Edit TNIP2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TNIP2 is highly significantly mutated in
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TNIP2 is significantly mutated in
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TNIP2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for TNIP2