TNFSF18 Back

tumor necrosis factor (ligand) superfamily, member 18

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of TNFSF18
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells.

Community Annotation of TNFSF18 Add / Edit TNFSF18: Annotations

No community annotations yet for TNFSF18.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TNFSF18 is highly significantly mutated in
(none)
TNFSF18 is significantly mutated in
(none)
TNFSF18 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TNFSF18