TNFAIP2 Back

tumor necrosis factor, alpha-induced protein 2

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NCBI Description of TNFAIP2

This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. The expression of this gene was shown to be induced by retinoic acid in a cell line expressing a oncogenic version of the retinoic acid receptor alpha fusion protein, which suggested that this gene may be a retinoic acid target gene in acute promyelocytic leukemia.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TNFAIP2 is highly significantly mutated in
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TNFAIP2 is significantly mutated in
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TNFAIP2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for TNFAIP2