TNC Back

tenascin C (hexabrachion)

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NCBI Description of TNC
This gene encodes an extracellular matrix protein with a spatially and temporally restricted tissue distribution. This protein is homohexameric with disulfide-linked subunits, and contains multiple EGF-like and fibronectin type-III domains. It is implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity, and neuronal regeneration.

Community Annotation of TNC Add / Edit TNC: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TNC is highly significantly mutated in
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TNC is significantly mutated in
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TNC is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TNC