TMSB4X Back

thymosin beta 4, X-linked

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NCBI Description of TMSB4X

This gene encodes an actin sequestering protein which plays a role in regulation of actin polymerization. The protein is also involved in cell proliferation, migration, and differentiation. This gene escapes X inactivation and has a homolog on chromosome Y.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TMSB4X is highly significantly mutated in
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TMSB4X is significantly mutated in
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TMSB4X is near significance in
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Click on a tumor type to see its full list of significant genes.